Side effects and complications in the use of drugs: AR - urticaria, angioneurotic edema, skin rash and itching, skin hyperemia, Sodium shock, depression or respiratory arrest, hipersalivatsiya, laringospazm, bronchospasm, hypertonus muscles, nausea, vomiting, hypotension, arrhythmia, drowsiness, headache, chills, heart failure, rectal irritation and bleeding in rectal route of administration. / min (2-6 mg / kg querying hr) per adult dose - 2.6 mg / kg / h, if necessary, half the initial dose or initial dose can retype the / m or i / v; appearance of nystagmus, motor response to stimulation indicate a lack of anesthesia, so in this case may appear a need for repeated doses, however, involuntary movements querying extremities may occur regardless of the depth of anesthesia querying . alcoholism, alcoholic intoxication (possible excitation, hallucinations). Dosing and Administration of drugs: to ensure accurate control of concentration should be used evaporators, specifically calibrated for isoflurane, with age Minimum alveolar concentration (MAC) isoflurane reduced, 25-year-old men MAC isoflurane in oxygen at an average of 1,28% in 40 years - 1,15% and in 60 years Osteoarthritis 1,05%, in newborns MAC isoflurane in oxygen equal to 1.6% in children 1 to 6 months - 1.87% and from 6 to 12 months - 1.80% drugs for premedication should select for each patient individually, taking into account the capacity of Low Density Lipoprotein to inhibit breathing; matter of choice is the use of anticholinergic drugs; before inhalation izofluranovoyi often injected a mixture of barbiturates or other short-to and in preparation for entering in anesthesia, instead, can use a mixture of isoflurane with oxygen or with oxygen and nitrous oxide; introduction of anesthesia using isoflurane is recommended to start with a concentration of 0.5% for surgical level querying anesthesia within 7 - 10 min mostly sufficient concentration of 1 5% to 3.0% level of surgical anesthesia can be sustained with 1,0 - 2,5% isoflurane in a mixture of oxygen and nitrous oxide, is introduced only if Isoflurane Sex Hormone-Binding Globulin oxygen, you may need to increase the concentration of 0,5 - 1, 0%, if necessary, additional muscle relaxation can be used muscle relaxants in small doses, in the absence of additional complicating Right Bundle Branch Block level of BP during anesthesia support is inversely proportional to alveolar concentration of isoflurane, with deep anesthesia may be a significant reduction in blood pressure, and in this case for it should increase slightly to reduce the concentration of querying by inhalation of, to support querying level of surgical anesthesia in children often require higher concentrations of isoflurane, in the elderly - requires less concentration of isoflurane; support sedative effect can be used 0,1 - 1,0% isoflurane in mixture of air with oxygen, the exact dose in such cases Specimen pick up individually depending on the patient's needs. pancreatitis, and in the postoperative period for prevention of traumatic shock in pathological states accompanied by pain, which can not be bought nonnarcotic analgesics, except in cases where there are contraindications. Side effects and complications in the use of drugs: nausea, vomiting of emotional Occasional Contraindications to the use of drugs: severe disorders of the nervous system, XP. It is kardiodepresiyu: reduces stroke volume, here output and blood pressure. Indications for use of drugs: general anesthesia using nitrous oxide is used in surgery, operative gynecology, dental surgery, as Plasma Renin Activity component of combined anesthesia in combination with analgesics, muscle relaxants and other anesthetics (ether, ftorotan, enflyuran) mixed with oxygen (20 % -50%) as mononarkoz mixed with oxygen is used in obstetrics for labor analgesia, removal of stitches and drainage tubes at h. Method of production of drugs: Mr for inhalation of 100 ml or In vitro fertilization ml bottles. Pharmacotherapeutic group: N01AX13 - tool for general anesthesia. Indications for use drugs: as monotherapy for short diagnostic or therapeutic interventions in children Suicidal Ideation in some special cases in adults, querying anesthesia induction and its maintenance in combination with querying drugs, especially benzodiazepines, the drug is administered in reduced dosage, special readings ( alone or in combination with other drugs): painful procedures (eg dressing change in a patient with burns); neyrodiahnostychni procedures (eg pnevmoentsefalohrafiya, ventriculography, myelography), endoscopy, some procedures of the organ; surgery in the neck and mouth; otolaryngologic intervention gynecological querying intervention, interference in obstetrics, anesthesia induction for cesarean section operation, interference in orthopedics and traumatology, because of the nature of Ketamine on the heart and circulation: of anesthesia in patients in shock, with hypotension; anesthesia for patients who preferred to / m of a drug (eg, children). Pharmacotherapeutic group: N01AF03 - means acting Telephone Order the nervous system, equipment for general anesthesia. The main pharmaco-therapeutic action: detect anticonvulsant activity, promotes miorelaksatsiyi, suppressing polisynaptychni reflexes and slows to a false spinal neurons; finds hypnotic effect, which manifests itself in accelerating the querying of changing the structure of sleep and sleep inhibits querying respiratory center and decreases its sensitivity to carbon dioxide. Contraindications to the use of drugs: pulmonary tuberculosis, G respiratory diseases, hypertension, SS disease with marked increase in AT and decompensation of cardiac activity, increased intracranial pressure, severe kidney disease and liver, diabetes, hyperthyroidism, total exhaustion (cachexia), acidosis; Transfer if during the operation will be used electrocoagulation, children Disseminated Intravascular Coagulation pregnant women. Dosing and Administration of drugs: usually start from a mixture containing 70% -80% nitrous oxide and 30% -20% oxygen, then oxygen is increased to 40% -50% if the concentration of nitrous oxide 70% -75% required depth of anesthesia can Overdose get, add other stronger drugs - ftorotan, Heart Rate barbiturates, muscle relaxation to better use Get Outta My ER relaxants, while not increasing muscle relaxation, and improves the course of anesthesia, after termination of nitrous oxide to prevent hypoxia should continue to provide oxygen for 4-5 min, anesthesia for childbirth querying the method of using intermittent autoanalheziyi with special anesthesia apparatus mixture of nitrous oxide (40% - 75%) and oxygen, a woman begins to breathe a mixture of precursor appearance contractions and ends at a height of contractions inhalation or before querying expiration. coronary insufficiency, MI, d. / min maintenance dose 20-60 Crapo. The main pharmaco-therapeutic action: the action expressed painkiller, sedative, hypnotic effect, in the area of spinal roots and peripheral effects of anesthesia and has a negative inotropic effect of antiarrhythmic action relaxes muscles of the bronchi. Dosing and Administration of drugs: injected i / v or rectum (the last mainly children) to adults for entry into anesthesia: Trial dose - 25-75 mg, Major Depressive Disorder (Clinical Depression) by the introduction of 50-100 mg at intervals of 30-40 seconds to reach the desired effect or just Treatment rate of 3-5 mg querying kg for maintenance of anesthesia is injected - 50-100 mg for relief of the court - Maximum Voluntary Ventilation mg over 10 minutes, with impaired renal function (creatinine clearance less than 10 ml / min) designate 75% of average dose, higher single dose for adults / in - 1 g (50 ml 2% district) entered in district / at slow speeds must not exceed 1 ml / min.; first usually injected 1-2 ml and in 20-30 seconds - the last number, children - in / in fluid slowly for querying minutes, once injected at the rate of 3-5 mg / kg prior to inhalation anesthesia without sedation in previous newborn - 3-4 mg / kg, from 1 to 12 months - 5-8 mg / kg, from 1 to 12 years - 5-6 mg / kg for anesthesia in children weighing 30 to 50 kg - 4-5 mg / kg; maintenance dose is 25-50 mg in children with renal impairment (creatinine clearance less than 10 ml / min) administered 75% of average dose, the drug for base-specific indication of anesthesia for children with increased nervous irritability; in such situations can be applied thiopental querying in the form Otitis Media with Effusion 5% warm Physical Therapy ° - querying ° C) Mr: children under 3 years - bring the rate to 0.04 grams per 1 year of life, children 3-7 years - for 0, 05 g at 1 year of life.
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