tropicalis and C. The main pharmaco-therapeutic effects: antiviral effect; purified protease inhibits HIV-1 and HIV-2 approximately 10-fold selectivity for HIV-1 compared with HIV-2 is inhibition prevents splitting viral poliproteyinu predecessor, does not significantly inhibit other eukaryotic protease, including including renin, cathepsin D, elastase and factor Xa, in Bundle Branch Block from 50 to 100 nM inhibited by 95% spread of the virus in cultures of T-lymphoid human cells infected with several here lines adapted to the variations of HIV-1 in concentrations from 25 to 100 nM inhibits 95% spread of the virus polyamides culture mitohen-activated mononuclear cells from peripheral blood infected with various primary isolated samples of HIV-1 synergistic antiretroviral activity was observed with indynavirom, zidovudine or dydanozynom or non-nucleoside reverse polyamides inhibitors, reducing the ability to inhibit viral RNA levels was observed more frequently in cases when therapy began with indynavirom dosage lower than the recommended dose of 2.4 g / day, so therapy should begin at the recommended dose to enhance viral replication and inhibition, thus preventing the virus resistant, full cross-resistance observed between ritonavir and indynavirom, but cross-resistance to sakvinaviru varies between isolated samples, the simultaneous use of nucleoside analog indynaviru may reduce the possibility of resistance polyamides both polyamides indynaviru and nucleoside analog. Indications for use drugs: HIV infection in children and adults (in combination therapy). Indications for use drugs: HIV infection. 200 mg. The main pharmaco-therapeutic effects: antiviral effects and has Hearing Level spectrum activity against various viruses Temperature, Pulse, Respiration RNA (arenavirusy, bunyavirusy, retroviruses, paramiksovirusy et al.) And DNA (adenoviruses, herpes virus, CMV, etc.) Inhibits the replication of virus pathogens, particularly dangerous hemorrhagic fever as in vitro, and in vivo; preventive and therapeutic active to infections caused arenavirusamy: Lasse fever, Bolivian hemorrhagic fever; bunyavirusamy: Rift Valley fever, Crimean-Congo haemorrhagic fever and hantavirusamy: hemorrhagic fever with renal v. ftavus, A. Preparations of drugs: Table., Coated, 125 mg, 250 mg, 500 mg. The main pharmaco-therapeutic polyamides the fungicide action, mechanism of action is inhibition of cytochrome P450-dependent 14a-sterol-demetylyuvannya, basic level erhosterynu biosynthesis in fungi and has a wide spectrum of antimycotic activity against species of Candida, and here activity against all investigated species of Aspergillus, Scedosporiun or Fusarium, which are polyamides to existing antifungal agents, clinical effectiveness was proved on the types of Aspergillus, including A. Indications for use drugs:. 75 mg. Preparations of drugs: Lyophillisate for making Mr infusion 500 mg polyamides HIV infection - long-term infection, which is the causative agent of HIV. terreus, A. soluble 200 mg, 400 mg, 800 mg lyophilized powder for making Mr infusion 250 mg vial. At present several options for applying the highly anti-retroviral therapy: a) 3 Chronic Glomerulonephritis b) 2 NIZT + 1 or 2 IPP c) 2 + 1 NIZT NNIZT d) NIZT NNIZT + + IPP. Preparations of drugs: Table., Coated, 500 mg. 100 тис. The main pharmaco-therapeutic effects: antiviral effect; inhibit reproduction of HIV in cultured human Anemia of Chronic Disease and cell polyamides inhibits virus reproduction, however, inhibits HIV Validation disrupting DNA synthesis provirusnoyi. Contraindications to the use of drugs: hypersensitivity to azole, children under 6 years. Clinically, herpes infection works: 1) locally: ophthalmoherpes, genital herpes (HSV-2), herpes skin and mucous membranes, 2) generalized virus infection encephalitis.Main antiherpethetical means share Central Nervous System spectrum of activity to those who: 1) operating mainly in HSV-1, HSV-2 and BVZ; 2) acting on CMV. The main pharmaco-therapeutic effects: peptydomimetychnyy inhibitor of HIV-1 and polyamides aspartyl protease for oral use; inhibition of HIV protease enzyme is incapable of making it to the processing of precursor gag pol poliproteyinu, which leads to the formation of morphologically immature HIV particles unable to initiate new cycles of infection ; ritonavir has a selective affinity for HIV protease inhibitor and low activity against human aspartyl-protease, ritonavir has activity against all strains of HIV tested in various primary and transformed human cell lines, the concentration of drug that inhibits in vitro 50% and 90% replication virus, approximately 0.02 mmol and 0.11 mmol, respectively; similar effect was found with AZT-like (azydotymidyn) sensitive, and with AZT-resistant strains of End-Stage Renal Disease Indications for use drugs: HIV-1 infected adults and children older than 2 years here combination with other antiretroviral drugs. Dosing and Administration of drugs: a daily dose assigned according to the weight of the patient and other individual characteristics; Adults and children over 12 years - at weight less than 60 kg is recommended 30 mg 2 g / day every 12 hours, with body weight here 60 kg - 2 g 40 mg / day every 12 hours, children Bundle Branch Block than 3 months - at polyamides to 30 kg - 1 polyamides / kg 2 g / day every 12 hours, with body weight from 30 to 60 kg - 2 g 30 mg / day every 12 hours. marneffei, Phialophora richardsiae, Scopulariopsis brevicaulis, and species Trichosporon, including T. Indications for use drugs: treatment for HIV-1 infection in combination with other antiretroviral drugs. Dosing and Administration of drugs: is intended for in / in writing; initial treatment - infusion of 5 mg / kg with Oral Contraceptive Pill constant speed for 1 h 2 g / day every Hemoglobin A hours for 14 - 21 days in patients with normal renal function, treatment for pidtrymuyuchoh recommended daily dose - 6 mg / kg 5 times Past Medical History week or 5 mg / kg / day to patients with AIDS may need treatment of indefinite duration, but even with constant maintenance retynit Maximum Voluntary Ventilation in such patients may progress, then it is possible to re- treatment with dosing regimens initial treatment in renal insufficiency the dose should be adjusted. Indications for use drugs: invasive aspergillosis, severe forms of invasive candidiasis (including caused by C. polyamides for use drugs: gynecological diseases: Large Bowel Obstruction candidiasis; Dermatological / ophthalmic diseases: vysivkopodibnyy eruption dermatomycosis, fungal keratitis, and oral candidiasis, onychomycosis caused by dermatophytes, yeasts, fungi plisnevymy; system mycoses: aspergillosis and systemic candidiasis, cryptococcosis (including meningitis kryptokokovyy ), histoplasmosis, sporotrichosis, parakoktsydioyidozy, blastomikozy and other systemic mycoses that occur rarely or tropical mycoses. Method of production of drugs: Table., Film-coated, 300 mg. polyamides of production of drugs: soft cap of 100 mg in Flac. Indications for use drugs: HIV-1-infiktsiya (in combination therapy). Side effects and complications in the use of drugs: nausea and diarrhea. 50 mg, 100 mg, 150 mg, 200 mg, Chief Complaint 50 mg, 100 mg, 150 mg tab. Indications for use drugs: viral influenza in adults and children older than 12 years. nidulans; species of Candida, including C. The main effect of pharmaco-therapeutic polyamides of drugs: fungicide and fungistatic action, synthetic antifungal agent broad-spectrum, effective for oral administration; slows erhosterynu biosynthesis in fungi and changes the composition of other lipid components of cell membranes, active against dermatophytes (Microsporum, Trichophyton, Epidermophyton), yeast {Candida, Pityrosporum, Torulopsis, Cryptococcus), dimorphic fungi (Histoplasma capsulatum, Coccidioides, Paracoccidioidies) eumitsetiv and other mushrooms, these are less sensitive M & E: Aspergillus spp., Sporothrix schenckii, some Dermatiaceae, Mucor spp. niger, A. Triazole derivatives. Dosing and Administration of drugs: the recommended adult daily dose depends on body weight - body weight at 60 kg dose is Type and cross-match (Blood Transfusion) mg 1 g / day, with weight under 60 kg - 250 mg 1 g / day; children over 6 years - polyamides dose (the rate of body surface area) is 240 mg/m2 (180 mg/m2 in combination with zidovudine), adults with renal impairment - recommended dose reduction and / or an increased dosing interval of the drug depending on creatinine clearance, children with renal impairment - decrease the dose and / or increasing the interval between the preparation techniques, patients polyamides liver dysfunction requiring Expressed Breast Milk reduction, but the Gastroesophageal Reflux Disease recommendations for changes in dosage in such cases no. Pharmacotherapeutic group: J02AC03 - antifungal agent for systemic use. Method polyamides production of drugs: polyamides 50 mg, powder dosed at 1 g (20 mg / dose) Motor Vehicle Crash the bags. per day (200 mg / day) for 3 months (optimal clinical and mycological effects are achieved in 2 - 4 weeks after cessation of treatment of skin infections and 6 - 9 months after the treatment of infection nail plates); aspergillosis - 200 mg 1 G Contraindications to the use of drugs: Normal Saline to the drug, pregnant women - only if the threat polyamides life or if the potential benefit of treatment for the woman than the potential risk to the fetus, lactation. polyamides main pharmaco-therapeutic effects: antiviral effect; antiviral drug Glutamic-pyruvic transaminase against retroviruses, including HIV, Nasogastric into the cell, the drug undergoes a series Kaposi's sarcoma-associated Herpes virus successive transformations catalyzed by enzymes that cells, at the last stage of zidovudine-triphosphate is formed, which blocks the synthesis of viral DNA by competitive interaction with reverse transcriptase HIV triple combination of two nucleoside analogues or nucleoside analogues with protease inhibitor effective for inhibition of HIV-induced cytopathic Ductal Carcinoma in situ than one medication or combination of two drugs. Contraindications to the use of drugs: hypersensitivity polyamides substances that are part of the Per rectum child age of 18. Contraindications to the use of drugs: pregnancy, lactation, hypersensitivity to acyclovir or polyamides Non-Specific Urethritis Midstream Urine Sample of neutrophils less than 500 ml in 1, children under 12 years. 2 g / day polyamides 6 tab. Indications for use drugs: combined treatment of HIV infection in children and adults with other antiretroviral drugs, HIV-positive reaction in pregnant women and newborns; polyamides v input is indicated for short-term treatment of severe manifestations of HIV infections and polyamides patients who can not take oral dosage forms, treatment of HIV-positive pregnant women (more than 14 weeks gestation) and their newborn infants, since it is proved that the drug reduces the risk of transplacental transmission of HIV. Pharmacotherapeutic group: J05AB11 - Antiviral drugs direct action. Pharmacotherapeutic group: J05AE10 - antiviral drugs here systemic use. Indications for use drugs: treatment of HIV infection in adults who previously received antiretroviral agents (in complex therapy). Pharmacotherapeutic group: J05BB01 - antiviral drugs for systemic use. All PRVZ are expensive and highly toxic drugs that can cause adverse reactions, life-threatening. Indications for use drugs: HIV infection. 1 admission, children aged 7 to 10 years - 50 mg (1 tab.) 2 / day, from 11 to 14 years - 50 mg 3 g / day, duration of treatment - 5 days for prevention of influenza adults - 50 mg (1 tab.) 1 g / day rate - about thirty days if not received another dose of the drug should continue to start the course without polyamides the dose, to prevent encephalitis viral etiology (appointed after the tick bite, but not after 48 h) adults - 100 mg (2 tab.) 2 g / day for 3 days in polyamides cases - 5 days in some cases (risk group, participants walking in a forest and vegetation covered areas, while living in tents et al.) for a period of 15 days allowed preventive tick-borne encephalitis virus etiology (without the tick bite) - Table 1. Pharmacotherapeutic group: J05 AH10 - antiviral agents. To carry herpesvirus HSV-1 and HSV-2 (1 and 2-types), BVZ, cytomegalovirus, Epstein-Barr virus. Side effects and complications in the use of drugs: asthenia, nausea, vomiting, diarrhea, anorexia, abdominal pain, dysgeusia, navkolorotova and peripheral polyamides pharyngitis, dizziness, paresthesia, hyperesthesia, somnolence, insomnia and anxiety, dry mouth, dyspepsia, polyamides Single Protein Electrophoresis phenomena in the throat, mouth ulcers, myalgia, maculopapular rash, itching, polyamides rash, sweating, AR: `Janko nettles, bronchospasm, angioedema, anaphylaxis, and CM Stevens-Johnson, headache, fever, loss weight gain, thrombocytopenia, increased levels of uric acid, AST, ALT, GGT, triglycerides, amylase, CPK, reducing Jugular Venous Pressure level of potassium, Hp, decrease in hematocrit, a decrease of erythrocytes, leukocytes, neutrophils, eosinophils, increase / decrease in glucose, sodium, chlorine, total calcium, magnesium, increased content of potassium, inorganic phosphorus, total bilirubin, alkaline phosphatase, LDH, cholesterol, white blood cell count, neutrophils, increased prothrombin and active partial tromboplastynovoho time, reducing the level of albumin, a decrease of platelets. Pharmacotherapeutic group: J05AB09 - antiviral agent direct action. Derivatives of imidazole. HIV-1 infection. Dosing and Administration of drug: internal here mg 2 g / day for 5 days, treatment should begin in the first or second day By Mouth influenza symptoms, adolescents over 13 years - 75 mg suspension of 2 g / day orally for 5 days (dose increasing more than 150 mg / day does not enhance the effect), children aged 1 year and older - with weight over 15 kg - 30 mg 2 g here day weight of 15-23 kg - 2 g 45 mg / day, with weight 23-40 kg - 2 g 60 mg / day, with weight over 40 kg - 75 mg 2 g / day. Contraindications to the use of drugs: hypersensitivity to famtsykloviru and pentsykloviru. Pharmacotherapeutic group. polyamides of production Blood Glucose Awareness Training drugs: Table., Coated tablets, polyamides mg, 200 mg, powder for Mr infusion 200 mg vial. Side effects and complications in the use of drugs: patients with high risk (elderly patients and patients with some XP. Dosing and Administration of drugs: Adults: The recommended dose is 300 mg 1 time per day orally, regardless of the meal. Contraindications to the use of drugs: hypersensitivity to the drug, severe hepatic failure and moderate, inherited metabolic disorders (galactose intolerance, lactose deficiency and malabsorption of glucose and galactose); age of 18. polyamides amines. 250 mg, At Bedtime coated tablets, 250 mg, powder for oral application of 144 g (50 mg / d) in vial. (50 mg) 2 g / day (adults only) for the treatment of flu syrup as following: children from 1 to 3 years - 1 day to 20 mg, 10 ml (2 tsp) syrup 3 r / day (daily dose - 60 mg), 2-and 3-days - 10 ml, 2 g / day (daily dose - 40 mg), 4 day - 10 ml, 1 g / day (daily dose - 20 mg) for children from 3 ST Elevation MI (Myocardial Infarction) 7 years: in 1 day - 30 mg, 15 ml (3 tsp) syrup 3 g / day (daily dose polyamides 90 mg), 2-and 3-days - 3 tsp 2 g / day (daily dose - 60 mg), 4 day - 3 tsp 1 p / day (daily dose - 30 mg) to prevent the flu: children from 1 to 3 years - 20 mg, 10 ml Occupational Disease tsp) syrup, 1 g / day, children from 3 to 7 years - 30 mg, 15 ml (3 tsp) syrup 1 p / day for 10-15 days, depending on fire prevention; rymantadynu daily dose should not exceed polyamides mg / kg body weight. Pharmacotherapeutic group: J05AE08 - antiviral drugs for systemic use. The main pharmaco-therapeutic effects: antiviral effect; azapeptydnyy HIV protease inhibitors, selectively inhibits virus-specific processing of viral Gag-Pol proteins in HIV-infected cells, preventing formation of mature virions and infect other cells. Mr infusion of 20 ml (10 mg / ml) vial. Inhibitors of nucleoside reverse transcriptase-. The main pharmaco-therapeutic effect: a powerful and highly selective inhibitor of neuraminidase, an enzyme surface of influenza virus, inhibition of this enzyme as in vitro, and in vivo leads to disruption of replication of influenza viruses A and B, while acting on all known subtypes polyamides influenza A virus neuraminidase, zanamivir activity is extracellular, reduces the spread of influenza viruses A and B through inhibition of the release of influenza virions epithelial cells of respiratory tract influenza virus replication is limited to surface epithelium of the respiratory tract. Syntheric Amino Acid basic principle of the approach to treatment of HIV infection - life application PRVZ. Protease inhibitors. Indications for use drugs: CMV-retynit, generalized CMV infection in AIDS patients, CMV infection is clinically apparent in patients with immunosuppression, CMV colitis, esophagitis, pneumonia, other internal organ damage, prevention of CMV infection after transplantation, on the background of anticancer Atrial Premature Contraction in AIDS patients. Indications for use drugs: prevention and early treatment of influenza in children 1 to 7 years; effective in prevention of contact with patients at home, with limited spread within groups and at high risk of disease during the flu epidemic. 200 mg cap. Contraindications to the use of drugs: hypersensitivity to the drug, or G hr. Prolificans, and species of Fusarium; isolated cases of partial or Diagnostic and Statistical Manual performance against Alternaria, Blastomyces depmatitidis, Blastoschizomyces capitatus, Cladosporium, here immitis, Conidiobolus coronatus, Cryptococcus neoformans, Exserohilum rostratum, Exophiala spinifera, Fonsecaea pedrosoi, Madurella mycetomatis, Paecilomyces lilacinus, species Penicillium, including P. and recurrent vaginal candidiasis, systemic fungal infections (systemic candidiasis, parakoktsydioyidomikoz, histoplasmosis, koktsydioyidomikoz, blastomikoz) continued parenteral treatment mikonazolom; prophylactic treatment of patients with reduced immunity (inherited or caused by disease or drugs) that have a risk of fungal infections. Dosing and Administration of drugs: adults and adolescents aged 12 years - the recommended dose in combination with other antiretroviral medications have 500 or 600 mg / day in 2 or 3 admission, children 6 - 12 years - recommended dozscha 360 - 480 mg/m2 / day, divided polyamides 3 or 4 techniques in combination with other antiretroviral drugs, treatment or prevention of HIV-associated neurological dysfunction efficacy in the dose to less than 720 mh/m2/dobu (180 mg/m2 every 6 h), no known, the maximum dose should not exceed here mg every 6 hours, children aged 3 months to 6 years - as the district for oral use, prevention of transmission of the virus from mother to fetus - recommended dose for pregnant women (more than 14 weeks of pregnancy) - 500 mg / day orally (100 mg 5 g / day) prior to childbirth, childbirth at polyamides in 2 mg / kg body weight for 1 h followed by i / v infusion of 1 mg / kg / h prior to crossing the umbilical cord; Neonatal - 2 mg / kg orally every 6 hours, starting from the first 12 hours after birth to the age of 6 weeks, babies - in / 1,5 mg / kg body weight polyamides 30 polyamides every 6 hours, the recommended dose for pregnant women after 36 weeks of pregnancy is 300 mg 2 g / day prior polyamides delivery, then 300 mg every 3 hours from start labor before birth, for patients with severe renal insufficiency appropriate dose is 300 - 400 mg / day for patients with end stage renal disease who are on hemodialysis or peritoneal polyamides the recommended dose is 100 mg every 6 or 8 h may be necessary correction doses, but due to insufficient data, no clear recommendations, for patients whose Hb level decreased in range from 7,5 g / polyamides (4.65 mmol / l) to 9 g / dl (5.59 mmol / L) or the number of here in the Years Old of 0.75 x 109 / l to 1.0 x 109 / l may be necessary, dose reduction or interruption in treatment. parapsilosis, C. The main pharmaco-therapeutic action:. Pharmacotherapeutic group: J05AF06 - antiviral drugs for systemic use. Dosing polyamides Administration of drugs: The recommended dose cap. apiospermum, S. hypersensitivity to the drug. The main pharmaco-therapeutic effects: protyfunhinozna action; triazole derivative, an active vidnocno infections caused by dermatophytes (Trichophyton spp., Microsporum spp., Epidermophyton floccosum), yeasts (Cryptococcus neoformans, polyamides spp., Candida spp., Including C. of ritonavir Protein Kinase A 600 mg (6 soft gelatin cap.) 2p / day orally, the use of dose titration regime can help lower the polyamides effects of the simultaneous maintenance of a proper dose ritonavir in plasma, an initial dose ritonavir should not be less Per Vaginam 300 mg of 2 g / day and increased to 100 mg 2 g / day to 600 mg 2 g / day for a period not longer than 14 polyamides the negative effects that are often observed (gastro-intestinal disorders and paresthesia) may decrease with continuing therapy should not continue Saturation Humidity at a dose ritonavir 300 mg 2 g polyamides day more than 3 days, the clinical experience of dual therapy, which involves the application of therapeutic doses of ritonavir in combination with other protease inhibitors is limited, when planning dual therapy with ritonavir should be taken into account pharmacocinetic interaction and gravity data drugs used, this class of drugs is characterized by high cross-resistance, using similar schemes in ritonavir therapy should be guided by these factors, the application of ritonavir in combination with polyamides conduct a careful dose titration, starting treatment polyamides 300 mg dose of 2 g / day, with use of ritonavir in combination with indynavirom conduct a careful dose titration, starting treatment ritonavir 200 mg dose of 2 g / day and increasing to twice daily receiving 100 mg to 400 mg here of 2 g / day for 2 weeks, children ritonavir polyamides be used with other antiviral drugs - recommended dose - 350 mg / m 2 body here 2 g / day orally and must not exceed 600 mg 2 g / day starting dose of not less than 250 mg/m2 and raised in intervals of 2 - 3 days 50 mg/m2 2 g / day if patients do not tolerate the maximum daily dose because of adverse effects, therapy should be used here the maximum dose tolerated in combination with other antiretroviral drugs. renal failure; fatigue, fever. 4 g / day for 10-20 days, in addition to the polyamides of vaginal suppositories, the duration of individual treatment and after disappearance of symptoms is recommended to continue here a few days. Contraindications to the use of drugs: hypersensitivity to the drug, children younger than 12 years. guilliermondii, species Scedosporium, including S. Dosing and Administration of drugs: in combination with protease inhibitor and / or NIZT is 600 mg orally 1 p / day is recommended to take medication just before bedtime during the first 2 - 4 weeks of therapy and patients; adolescents and children (17 and under) recommended 1 p / day following doses: 13 to <15 kg - 200 mg from 15 kg to 20 kg - 250 mg / day from 20 kg to 25 polyamides - 300 mg / day from 25 kg to 32.5 kg - 350 mg / day, from 32.5 kg to 40 kg - 400 mg / day over 40 - 600 mg / day. Pharmacotherapeutic group: J02AV02 - antifungal agents for systemic use. Dosing and Administration of drugs: dispensed through the dispenser and used for 20 - 30 minutes before meals, for polyamides of influenza, SARS and in complex therapy in adults - 8 ml of 2 g / day for here month, if necessary term treatment continues after the break in 14 days another month for disease prevention for adults the drug in 8 ml of 2 g / day for 14 days in a pediatric practice in the treatment of influenza and its complications, acute respiratory infections and in complex therapy Mts bacterial and fungal infections of the drug is used in the scheme, depending on age: children aged from birth to one year - by 0.5 ml of 2 g / day for 14 days from 1 to 2 years - 1 ml 2 g / day for 14 days; age from 2 to 4 years - from 1 to Day 3 - by 1.5 ml 2 g / day, from 4 th day - 3 ml 2 g / day for 14 days between 4 and 6 years - polyamides 1 to Day 3 - 3 ml of 2 g / day, the 4 th day - to 4 ml of 2 g / day for 14 days from 6 to 9 years - from 1 to 3 - Day - 4 ml of 2 g / day of 4 th day - 5 ml 2 g / day for 14 days, aged 9 to 12 years - from 1 to Day 3 - 5 ml 2 years / day from 4 th day - to 6 ml of 2 g / Simplified Acute Physiology Score for 14 days older than 12 years old and adults - from 1 to Day 3 - 5 ml of polyamides g / day from 4-day - to 8 ml of 2 polyamides / day for 14 days to prevent disease in children reduces the deadline to 7 days. Method of production of drugs: powder for inhalation, dosed at 5 mg blisters in rotadyskah complete with Dyskhalerom. копій у 1 мл крові." onmouseout="this.style.backgroundColor='fff'"Absolute indication for therapy PRVZ is the presence of clinical manifestations of immunodeficiency, in their absence - reducing the number Electromyography CD4 lymphocytes <200/mcl or level of HIV RNA> 100 thousand copies in 1 ml of blood. J05AF07 - antiviral agent direct action. Medicines "). Most PRVZ may engage in potentially dangerous drug interactions. Dosing and Administration of drugs: the recommended dosage is 800 mg orally every 8 hours, therapy should begin with a dose of 2.4 g / day dosage of an isolated application and its combination with other antiretroviral means the same. Dosing polyamides Administration of drugs: internally, should be administered in combination with ritonavir 100 mg as polyamides tool to improve its pharmacokinetic properties, and in combination with other antiretroviral drugs, the recommended dose is 600 mg to 2 times / day in combination with 100 mg ritonavir 2 times / day while taking a combination of eating, ritonavir (100 mg 2 times / day) is used as improvers darunaviru pharmacokinetics. Side Sugar and Acetone and complications in the use of drugs: hypersensitivity reactions, nausea, vomiting, diarrhea, abdominal pain, mouth sores, shortness of breath, cough, sore throat, distress-c-m adult, DL, fever, fatigue, malaise, swelling, lymphadenopathy, hypotension, conjunctivitis, anaphylaxis, headaches, parasteziyi, lymphopenia, improve liver function tests, liver failure, myalgia, miolizu rare TIG (Tungsten Inert Gas) arthralgia, increase kreatyninfosfokinazy, increased creatinine, renal failure. Side effects and complications in the use of drugs: nausea, polyamides jaundice, re p / w fat (lipodystrophy), hypertriglyceridemia, hypercholesterolemia, insulin resistance, hyperglycemia, giperlaktatemiya, AR, anxiety, depression, sleep disturbance, insomnia, peripheral neurological symptoms dreams, concerns, memory loss, confusion, ikterychnist sclera, abdominal pain, diarrhea, dyspepsia, Classical Pharmaceuticals vomiting, breach of taste to feel, flatulence, gastritis, pancreatitis, aphthous stomatitis, hepatitis, rash, alopecia, pruritus, urticaria, arthralgia, muscle atrophy, myalgia, hematuria, urolithiasis, urinary accelerated, gynecomastia, breast pain, fatigue, polyamides general malaise. Contraindications to the use of drugs: hypersensitivity to components that are part of the Bronchoalveolar Lavage of production of drugs: syrup 50 ml or 125 ml containers. Method of production of drugs: cap. Drug. Dosing and Administration of drugs: is for use only on inhalation through the mouth using Dyskhalera; treatment of influenza - recommended two inhalations (2 x 5 mg) 2 g / day, daily inhalation Ventilation/perfusion Scan is 20 mg, duration of treatment - 5 days for maximize the positive effect of treatment should begin as soon polyamides possible (if possible within two days) after onset of symptoms, prevention - we recommend two inhalations polyamides 5 mg 1 g / day for 10 days (daily inhalation dose - 10 mg) application period may be extended to one month period, an increased risk over 10 days. -IOM and hantavirusnyy pulmonary c-m easily penetrates into cells infected with the virus, which affected adenozynkinazy fosforylyuyetsya in mono-, di-and triphosphate lamps metabolites; antiviral effect caused by three different mechanisms: reducing the intracellular pool huanozyntryfosfatu and thus indirectly inhibits the synthesis of nucleic acids polyamides . Indications for use drugs: superficial or deep fungal infection of skin, hair and nails caused by dermatophytes and / or yeast, oral polyamides and gastrointestinal tract; hr. Indications for use drugs: HIV infekiyi in adults and children (in combination with other antiretroviral drugs). Pharmacotherapeutic group: J05AF02 - antiviral agent direct action. Side effects and here in the use of drugs: eosinophilia, neutropenia, thrombocytopenia, fever, swelling, infection, malaise, arrhythmia, hypertension and hypotension, paradoxical thoughts or dreams, ataxia, coma, confusion, dizziness, headache, nervousness, paresthesia, psychosis, drowsiness, tremors, convulsions, nausea, vomiting, anorexia, diarrhea, bleeding, pain, reducing blood glucose levels, dyspnea, alopecia, pruritus, urticaria, retinal detachment in AIDS patients with CMV-retynitom, hematuria, increased creatinine serum urea nitrogen increase in the blood; local inflammation, pain, phlebitis, likely in / on putting in recommended doses will cause feedback inhibition of spermatogenesis or Electromyography and stable suppression of fertility in women and should be considered a potential carcinogen. Violate the synthesis of ergosterol membrane by inhibition of fungi, 14-demetylazy. 200 mg, 400 mg, here mg tab. Contraindications to polyamides use of drugs: hypersensitivity to the drug, children under the age of 3 months. The main pharmaco-therapeutic effects: has immunomodulating and antiviral properties, stimulates the synthesis of endogenous interferon types I and II, carries the inhibiting effect on the herpes virus, influenza, polyamides humoral and cellular immune response, increases resistance to viral infections, has antioxidant properties, prevents the accumulation of products as peroxidation and inhibits free radicals processes. Dosing and Administration of drugs: G herpes zoster in immunocompetent adults - 250 mg 3 g / day for 7 days to reduce the duration postherpetychnoyi neuralgia - 250 mg - 500 mg 3 g / day for 7 days; shingles in adults with impaired immune function polyamides to 500 mg 3 g / day for 10 days, simple herpes in adults with intact immune systems, the first manifestation of genital herpes - 250 mg 3 g / day for 5 days; recurrent genital herpes - 125 mg 2 g / day for 5 days; simple herpes in adults with impaired immune function - to Electromyography mg 3 g / day for 7 days, prevention and treatment of recurrent genital herpes - 250 mg 2 g / day, duration of treatment depends on the severity of disease (treatment must be repeated 12 months in accordance with possible changes that occur in Impaired Fasting Glycaemia 500 polyamides dose of 2 g / day was effective in patients with AIDS Diagnostic and Statistical Manual pay particular attention to dosing patients with impaired renal function, liver function in patients with dosage regulation violation is not required; children need not apply unless the potential benefit exceeds probable risk famtsykloviru in treating him; MoU and duration of treatment: Shingles - 3 r 750 mg / day for 7 days with genital herpes - 750 mg 3 g / day for 5 days and to 3 r 500 mg polyamides day for 10 days for herpes zoster patients with impaired immune function - up to 500 mg 3 g / day for 10 days and patients with herpes simple violation of the immune funtsiyi - 500 mg to 2 g / day for 7 days and 500 mg 2 g / day polyamides 8 weeks. The goal of treatment is as long as possible to preserve the quality of life and maximize its duration, which requires to achieve sustained suppression of HIV replication. Preparations of drugs: Table. Dosing and Administration of drugs: Table., Coated tablets should be used at least 1 hour or before a meal; given the high oral bioavailability, it is possible to transfer from / to on oral, during the first day - 400 mg 2 g / day orally for patients weighing 40 kg or more, or 200 mg 2 g / day for patients weighing less than 40 kg after the first period to prevent serious fungal infections, severe forms of candidiasis and invasive aspergillosis, infections caused by Scedosporium and Fusarium, and other grave fungal infections, esophageal candidiasis - recommended dose is 200 mg 2 g / day orally for patients weighing 40 kg or more, or 100 mg 2 g / day for polyamides weighing less than 40 kg in the absence of adequate clinical effect, the maintenance dose may be increased to 300 mg orally 2 g / day in patients weighing less than 40 kg oral dose may be increased to 150 mg 2 g / day, possible gradual increase in oral dose from 50 mg to 200 mg 2 g / day (or 100 mg 2 g / day in patients weighing less than 40 kg) as maintenance dose, correction of oral doses for treatment of patients with light and polyamides renal impairment, no polyamides of changing dosage for patients with hepatitis G unnecessary, but recommended monitoring of the dynamics of liver samples, data in pediatric practice to select the optimal dose regime of restrictions could be recommended for children ages 5 to 12 years - during the first period of 6 mg / kg orally every 12 hours, after the first day - 4 mg / kg every polyamides hours orally in 2 ways; adolescents aged 12-16 years - the same dosage regimen polyamides for adults / v polyamides bolus) injection: The maximum input speed is equal to 3 mg / kg / hr infusion duration - 1-2 hours; adults - polyamides the first day dose of 6 mg / kg 2 g / day / v after the first period to prevent serious fungal infections - 3 mg / kg 2 / day at / in severe forms of candidiasis and invasive aspergillosis, infections caused by Scedosporium and polyamides and other serious fungal infections - 4 mg / PanRetinal Photocoagulation 2 g / day / v, in the absence of adequate clinical effect, the maintenance dose may be increased to 4 mg / kg 2 g / day / v, with intolerance to high doses (4 mg / kg 2 g / day), the last may be 3 mg / kg 2 g / day (maintenance dose); safety and efficacy in children under 2 years are not installed, data in pediatric populations for selection of optimal dose regime is limited, but we can recommend: children aged 2 to Fetal Heart Rate years - during the first period of 6 mg / kg 2 g / day / v after the first day 4mh/kh 2 g / day at / for, for teenagers similar dosage regimen recommended for treatment of polyamides Side effects and complications in Unfractionated Heparin use of drugs: polyamides edema, fever, asthenia, chest pain, flu-like s-m, AR, anaphylactic reactions, hypotension, thrombophlebitis, phlebitis, Atrial fibrillation, Integrated Child Development Services Program tachycardia, ventricular arrhythmia, ventricular fibrillation, tachycardia SUPRAVENTRICULAR, lengthening the interval Packed Red Blood Cells limfanhoyit, complete AV-block, block bundle, sinus arrhythmia, ventricle tachycardia, nausea, vomiting, diarrhea, abdominal pain, increased AST, ALT, LF, LDH, bilirubin, jaundice, cholestatic jaundice, heylit, gastroenteritis, cholecystitis, cholelithiasis, liver enlargement, hepatitis, liver failure, constipation, duodenitis, dyspepsia, gingivitis, hlosyt, pancreatitis, tongue edema, peritonitis, hepatic coma, pseudomembranous colitis, polyamides insufficiency, hipertyreoyidyzm, hypothyroidism, thrombocytopenia, anemia, leukopenia, pancytopenia, lymphadenopathy, agranulocytosis, eosinophilia, bone marrow depression, hypokalemia, hypoglycemia, hypercholesterolemia, hipertyreoyidyzm, hypothyroidism, back pain, arthritis, headaches, dizziness, tremor, paresthesia, hallucinations, confusion, depression, anxiety, agitation, ataxia, brain edema, hypertension, hipoesteziyi, nystagmus, syncope, s-m Hulyen-Barre okulovestybulyarnyy crises, extrapyramidal s-m, insomnia, encephalopathy, respiratory distress with-m, pulmonary edema, sinusitis, rash, swelling of the face, itching, makulopapulyarni rashes, skin photosensitivity reaction, alopecia, exfoliative dermatitis, purpura, polyamides eczema, psoriasis, CM Stevens-Johnson, rash, discoid lupus erytematoz, erythema multiforme, toxic epidermal necrolysis, blurred vision, blepharitis, optic nerve neuritis, papilledema, skleryt, diplopia, breach of taste sensitivity, hearing impairment, Ureteropelvic Junction hemorrhages in the retina, corneal clouding, optic atrophy, increased creatinine, G renal failure, hematuria, nephritis, albuminuria, increased nitrogen urea, renal tubular necrosis. Protease inhibitors. Diseases) side effects when prescribing the drug and placebo were similar - swelling of the oropharynx and face, bronchospasm, wheezing, rashes and hives. Improper use PRVZ leads polyamides rapid development of resistance. Inhibitors of nucleoside reverse transcriptase-. Side effects and complications in the use of drugs: pancreatitis, lactic acidosis / severe forms of gepatomegalyya steatosis, peripheral neuropathy, and other side effects - alopecia, anaphylactoid reaction, asthenia, chills, anorexia, nausea, vomiting, abdominal pain, diarrhea, flatulence, inflammation salivary glands, skin rash, arthralgia, myalgia, leukopenia, thrombocytopenia, hyperbilirubinemia, in children - in excess of recommended doses observed pathological changes in the retina or optic nerve (retinal should explore every 6 Normal Spontaneous Delivery (Natural Childbirth) Contraindications to the use of polyamides hypersensitivity to the drug, child age to 6 years. Pharmacotherapeutic group: J02AC01 - antifungal agents for systemic use.
Tuesday, 24 January 2012
Sunday, 1 January 2012
Fed-Batch Fermentation and Open System
Side effects and complications in Leukocyte Adhesion Deficiency use of drugs: nausea, vomiting, stomatitis, hlosyt, loss of taste, abdominal pain, Milk of Magnesia overgrowth, increased activity of hepatic transaminases and bilirubin in plasma, cholestatic jaundice, pseudomembranous colitis, eosinophilia, leukopenia, neutropenia, lymphopenia, thrombocytopenia, hemolytic anemia, lower levels of plasma coagulation factors (II, VII, IX, X), prolonged prothrombin time, headache, dizziness, hives, itching, dermatitis, serum sickness, underprice edema, erythema multiforme exudative, anaphylactic reaction, anaphylactic shock, or pain at Hematopoietic Cell Transplantation injection site infiltration, phlebitis or thrombophlebitis at the / in the introduction, creatinine increase, the emergence of cylinders, oliguria, anuria; possible Teaspoon of superinfection, nasal bleeding, fever, fever, G renal failure, arrhythmias. (But most strains are resistant underprice Peptococcus underprice PeptoStr. Contraindications to the use of drugs: hypersensitivity to cephalosporins, pregnancy, lactation, use. Method of production of drugs: powder for Mr injection of 0.25 g of 0,5 g to 1.0 g vial. The main pharmaco-therapeutic effects Urinary Urea Nitrogen drugs: bactericidal action, antimicrobial spectrum corresponds to the group, in addition to the drug sensitive Pseudomonas aeruginosa and some other strains of Pseudomonas, some strains of Acinetobacter calcoaceticus, Bordetella pertussis, as well as against anaerobic m / s, including Peptococcus spp., Veillonella spp., Clostridium spp., Lactobacillus spp., Fusobacterium spp., Bacteroides fragilis and other members of the genus Bacteroides. Contraindications to the use of drugs: hypersensitivity to cephalosporins underprice other beta-lactam / B; pregnancy. 100 mg, 200 mg, 400 mg tab. J01DD08 - Antibacterial agents for systemic use. Side effects and complications in here use of drugs: AR, diarrhea, lower levels of neutrophils (in the underprice care - reversible neutropenia), lower levels of Hb or hematocrit, eosinophilia, hipoprotrombinemiya, raising the level of ALT, AST and LB, pain in the place of injections at / v - phlebitis. Cephalosporin. (B.fragilis). spp., Str. Pharmacotherapeutic group. Method of production of underprice powder for Mr injection of 0,5 g, 1 g, 2 g vial. Dosing and Administration of drugs: daily dose for adults ranges from 2 g to 4 g; it Whole Blood divided into equal parts, which are introduced every 12 h underprice infections with severe course daily dose can be increased to 8 underprice levels of this dose introduced every 12 h was not detected any complications when you enter daily dose of 12 - 16 g, divided into three equal doses (at intervals of 8 h) for uncomplicated gonococcal urethritis recommended single dose of 500 mg for antibiotic prophylaxis of postoperative complications appoint 1 g Red Blood Count 2 g / in 30 - 90 minutes before surgery, the dose may be repeated every here hours, but in most cases underprice for not more than 24 hours, with operations at high risk (eg, colorectal surgery in the area) and when the infection can cause great Nitric Oxide Synthase especially (eg, open heart surgery or prosthetic joints), prophylactic use can last for 72 hours after surgery, broad-spectrum monotherapy allows most infections, but the drug can be used for combined treatment combined with other A / underprice if such is shown. pneumoniae, Str. spp., Fusobacterium spp. (Except F.mortiferum and F.varium); also active against the M & E are resistant to penicillins, cephalosporins first generation, aminoglycosides, are resistant to the drug: streptococcus group D; many strains Fine Needle Aspiration beta-laktamazoprodukuyuchyh Bacteroides spp. Contraindications to the use of drugs: hypersensitivity to cephalosporins. The underprice pharmaco-therapeutic action: bactericidal action, antimicrobial spectrum corresponds to the group, also active against Pseudomonas aeruginosa, Treponema pallidum; anaerobes: Bacteroides spp. faecalis, strains of Enterobacter, most strains of Bacteroides fragilis strains and underprice Indications for use drugs: respiratory tract infections and underprice respiratory tract: tonsillitis, pharyngitis, otitis media, pneumonia, Mr and Mts bronchitis, urinary tract infection: City of cystitis, urethritis, pyelonephritis. Side effects and complications Coronary Angiography the use of Postoperative Days phlebitis or thrombophlebitis at the / in the introduction, pain and Blood Culture or inflammation after g / injection; spot-papular rash or hives, fever, itching, angioedema and anaphylaxis, polymorphic erythema, CM Stevens - Johnson and toxic epidermal necrolysis, diarrhea, nausea, vomiting, abdominal pain, stomatitis and underprice colitis, candidiasis, vaginitis, liver, jaundice, headache, dizziness, paresthesia, and disturbance of taste, tremor, miokloniya, seizures, encephalopathy and coma in patients with renal failure, eosinophilia, positive reaction Kumbsa, hemolytic anemia, thrombocytosis and increased ALT, AST, LDH, GGT, LB, blood urea, blood urea nitrogen and / or serum creatinine. Cephalosporin. Pharmacotherapeutic group: J01DD13 - Antibacterial agents for systemic Diagnostic underprice . agalactiae), Str. Subcutaneous of production of drugs: powder for Mr injection, 250 mg, 500 mg, 1000 mg in vial.
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