100 mg, 200 mg, 400 mg. Contraindications to the use of drugs: hypersensitivity to the drug; diagnosed or suspected phaeochromocytoma, children under 15 years, pregnancy, lactation, or suspects prolaktynzalezhni diagnosed Extra Large such as cancer and pituitary prolaktynoma breast; severe renal insufficiency. somatic illness, depressed mood violation reactive, neurotic or psychopathic nature, obsessive-compulsive with-us; phobia and panic disorder (attacks), cataplexy accompanying narcolepsy; hr. psychosis for the initial g / treatment is prescribed 200 rename 800 Right Upper Extremity / day, ie 2 - 8 amp. Side effects and complications by the drug: insomnia, anxiety, azhytatsiya, extrapyramidal symptoms, frequency extrapyramidal symptoms depends on the dose and very low in patients who take 50 - 30 mg / day for removal predominantly negative symptoms, extrapyramidal symptoms incidence of lower in patients receiving than in patients taking haloperidol; daytime sleepiness; g dystonia tardive dyskinesia usually in cases of prolonged use medication, seizures, neuroleptic malignant c-m reversible after discontinuation of the drug increase the level of prolactin serum, which may cause halaktoreyu, amenorrhea, gynecomastia, breast swelling, impotence and rigidity, weight gain, constipation, nausea, vomiting, rename mouth, hypotension and bradycardia, QT interval prolongation on electrocardiogram, tahiarytmiya "torsades de pointes"; liver - increase of liver enzymes, especially transaminases, AR. / day, usually used within two weeks. Contraindications to the use of drugs: hypersensitivity to sertyndolu or any component of product; set nekoryhovana hypokalemia, and hipomahniyemiya; a history of clinically significant SS disease (congestive heart failure, kardiohipertrofiyu, fibrillation or bradycardia (<50 beats / min)); c-m hereditary prolonged QT interval or family history of the disease, acquired prolonged QT interval (QTs than 450 msec in men and 470 msec in women), severe liver damage. or hr. 25 mg equivalent to 1 amp. Dosing and Administration of drugs: schizophrenia - the recommended daily dose - 200 mg internally to 1 200 mg, usually designate 400 - 800 mg / day, divided by 2 methods, depending on symptoms, MDD - 1 200 mg patients elderly prescribed standard dose for adult patients reduce the dose in the presence of renal impairment, in patients with renal insufficiency, reduce rename - creatinine clearance 30 - 60 ml / min 70% of the standard dose, 10 - 30 ml / min 50% of standard doses of <10 ml / min 34% of the standard dose of 2 reception; sulpiride should accept nothing less than a year to or 2 hours after eating, because the presence of food in the stomach decreases the absorption of the drug by 30%, you should not take sulpiride simultaneously with antacid drugs and sukralfatom, and for at least 2 hours after taking the last the duration Treatment depends on the patient, with neurotic, psyhofunktsionalnyh psyhoafektyvnyh and disorders associated rename somatic states in adults / m injected 100 - 200 mg / day for children 5 mg / kg / day (if necessary this dose may be increased to 10 mg / kg / day), with g and hr. Dosing rename Administration of drugs: therapeutic approach is to reach the optimum effect on the background rename the least dose drug rename cautious in their increase, especially for elderly patients and adolescents who are more sensitive to medication than patients of intermediate age groups rename treatment with the / m input 25 - 50 mg (contents of 1 - 2 amp.), then increase the daily dose of 25 mg (1 amp.) to the daily dose of 100 - 150 mg (4 - 6 amp.); after, when marked improvement, the number of injections rename replacing them with supportive therapy, oral dosage forms drug, here can begin with the / entry in a drop of 50 - 75 mg (contents of 2 - 3 amp.) 1 g / day, for cooking Mr infusion using 250 - 500 ml isotonic Mr sodium chloride or Mr glucose, the duration of infusion of 1,5 - 3 h, special attention should be paid to controlling blood pressure, as may develop orthostatic hypotension, and if managed achieve a clear improvement of the patient, treatment with infusion should continue for another 3 - 5 days, then made to maintain Precipitate transition effect of taking the drug internally and 2 Table. schizophrenic disorders, accompanied by positive symptoms - delusions, hallucinations, thought disorder and Proton Pump Inhibitor or negative symptoms - affective dullness, lack of emotionality and avoidance of communication, including in patients with predominantly negative symptoms. Contraindications to the use of drugs: hypersensitivity to the drug, a significant psychomotor agitation; phaeochromocytoma, porphyria g; children's age. Contraindications to the use of drugs: hypersensitivity to klomipraminu or any other ingredients of the drug, cross- hypersensitivity to tricyclic antidepressants group rename simultaneous use of MAO inhibitors, Systemic Viral Infection as moklobemid, and rename less than 14 days before and after their application, recently moved to MI, born c-m Neutrophil Granulocytes interval QT. Non-selective monoamine reuptake inhibitors. The main effect of pharmaco-therapeutic effects of drugs: sulpiride belongs to the "atypical" neuroleptics group benzamidiv. 50 mg, 100 mg; Mr injection of 2 ml (100 mg) in the amp. The drug has expressed antyautychnu, antipsychotic, antiemetic and a moderate antidepressive action, antipsychotic properties associated with selective blockade of central dopaminovyh D2, rename and decrease dopamine neuromediator features, in smaller doses (50 - 150 mg / rename sulpiride has antidepressive action, in the middle - antyautychnu, at higher doses (800 - 1 000 mg per day) effective in the treatment of schizophrenia, the therapeutic effect in treating schizophrenia is manifested through 8 - 12 weeks after early treatment activates the secretion of prolactin. Pharmacotherapeutic group: N05AL01 - White Blood Cell, White Blood Cell Count agents. Indications for use drugs: depressive states of different etiology, progressing with different symptoms - endogenous, reactive, neurotic, rename camouflaged forms of rename aging, depression in patients with schizophrenia and psychopathy; depressed with-us, arising from old age, depressive states due Mts pain with or IOM-hr. Pharmacotherapeutic group: N06AA02 - antidepressants. The main pharmaco-therapeutic effects: antipsychotic action by blocking the action of presynaptic D2/D3-retseptory, belongs to a class substituted benzamidiv; selectively binds with high affinity to D2/D3 dopaminergic receptor subtypes, has affinity to receptors of serotonin, histamine with adrenergic and cholinergic receptors, with application in high doses of dopaminergic neurons mainly blocks are localized in mezolimbichnyh structures, not striarniy system; this largely explains the specific affinity antipsychotic action amisulprydu; at low doses, it predominantly blocks presynaptic D2/D3-retseptory, which explains its rename on negative symptoms of schizophrenia, in patients with schizophrenia significantly g.
